Antibodies

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  1. Plexin domain containing protein 2 (PLXDC2), a cell surface transmembrane protein, is expressed in many tissues including haemotopoeitc stem cells, neural stem cells, pluripotent stem cells, and tumor cells. PLXDC2 may play an important role in neuronal growth, stem cell development, angiogenesis, and cancer cell growth. Recently PLXDC2 was reported a good cell surface marker as human haemotopoetic stem cells (1).

    PLXDC2 has been reported as a receptor for pigment epithelium derived factor (PEDF) (2) or as an activating ligand for adhesion G-protein coupled receptor D1 (Adgrd1) (3). Also PLXDC2 was thought as a novel interaction partner and an entry receptor for rhesus monkey rhadinovirus (RRV) 4). The gene expression level of PLXDC2 was elevated in the peripheral blood of stroke patients (5) or in mouse bone marrow-derived macrophages in response to Helicobacter pylori (6). The protease BACE1 (β-Site APP Cleaving Enzyme), a major drug target in Alzheimer's disease, cleaves the amyloid precursor protein (APP) as well as PLXDC2 as one of several other substrates (7).

    Antibody Citation:

    1. Sakuma C. et al. Western blotting of native proteins from agarose gels Biotechniques Apr 6 (2022).
    2. Akuta T. et al. A new method to characterize conformation-specific antibody by a combination of agarose native gel electrophoresis and contact blotting. Antibodies 11(2), 36. (2022).
    From $210.00
    Catalog: 2631, Format : Unconjugated
    Applications: ELISA
  2. From $210.00
    Catalog: 2566, Format : Fc tag
    Applications: ELISA
  3. From $418.80
    Catalog: 1151, Format : Unconjugated
    Applications: Functional Assay, IHC, ELISA
  4. From $180.00
    Catalog: 2141, Format : Unconjugated
    Applications: Flow Cytometry, WB, ELISA
  5. From $90.00
    Catalog: 2026, Format : Unconjugated
    Applications: ELISA
  6. From $210.00
    Catalog: 2341, Format : Unconjugated
    Applications: Flow Cytometry, ELISA
  7. From $118.80
    Catalog: 2341B, Format : Biotin
    Applications: Flow Cytometry, ELISA
  8. From $210.00
    Catalog: 2481, Format : Unconjugated
    Applications: ELISA
  9. The clone was selected from our CDR mutant library made from a humanized clone hN2 using our state of the art engineering method: Stage Enhanced Maturation (STEM) technology.

    From $210.00
    Catalog: 2644, Format : Unconjugated
    Applications: Functional Assay, ELISA
  10. Coronaviruses belong to a large family of protein enveloped positive-strand RNA viruses that are known to cause upper respiratory, gastrointestinal, central nervous system diseases in animals and human (1). One of the main proteins on viral envelop is a heavily glycosylated spike (S) protein (2). Trimeric S protein is involved in host receptor angiotensin-converting enzyme 2 (ACE2) recognition and mediates viral entry into cells. It is the principle antigenic determinant of neutralizing antibodies (3). S protein is recognized by humoral immune response during infection leading to inflammatory response. Homotrimeric S protein is a class I fusion protein that forms large protrusions from the virus surface and undergoes a significant structural rearrangement to fuse the viral membrane with the host-cell membrane once it binds to the host receptor (4).

    From $210.00
    Catalog: 2581, Format : His tag
    Applications: ELISA
  11. Coronaviruses belong to a large family of protein enveloped positive-strand RNA viruses that are known to cause upper respiratory, gastrointestinal, central nervous system diseases in animals and human (1). One of the main proteins on viral envelop is a heavily glycosylated spike (S) protein (2). Trimeric S protein is involved in host receptor angiotensin-converting enzyme 2 (ACE2) recognition and mediates viral entry into cells. It is the principle antigenic determinant of neutralizing antibodies (3). S protein is recognized by humoral immune response during infection leading to inflammatory response. Homotrimeric S protein is a class I fusion protein that forms large protrusions from the virus surface and undergoes a significant structural rearrangement to fuse the viral membrane with the host-cell membrane once it binds to the host receptor (4).

    From $210.00
    Catalog: 2672, Format : His tag
    Applications: ELISA
  12. From $210.00
    Catalog: 2460, Format : His tag
    Applications: ELISA
  13. From $210.00
    Catalog: 2660, Format : His tag
    Applications: ELISA
  14. From $210.00
    Catalog: 2664, Format : His tag
    Applications: ELISA
  15. From $175.00
    Catalog: 2676, Format : His tag
    Applications: ELISA
  16. From $175.00
    Catalog: 2680, Format : His tag
    Applications: ELISA
  17. From $175.00
    Catalog: 2692, Format : His tag
    Applications: ELISA
  18. From $175.00
    Catalog: 2688, Format : His tag
    Applications: ELISA
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