We are Abwiz Bio
Abwiz Bio was founded in San Diego in September 2012 by Toshi Maruyama and CJ Okumura to make the antibodies conventional methods miss — and to keep engineering them until they work in the assay or program they are meant for.
The lab runs on two platforms we built ourselves. RabWiz™ pairs rabbit immunization with phage display: patented WizAmp™ library construction (US Pat. 9,890,414) and a phagemid vector that displays the cysteine-rich rabbit Fabs other systems drop, so rare clones against GPCRs, ion channels, phospho-sites and small molecules are captured and selectable. STEM™ staged affinity maturation has taken client leads from nanomolar to picomolar — up to 1,338-fold — and our humanization workflow has retained binding on 15 of 15 antibodies. Over 400 immune libraries and 25 peer-reviewed publications since 2012.
Every project is scoped and run by the scientists on this page — the person who reads your inquiry is the person who would do the work. You own the antibodies we make for you, with no downstream royalties; an NDA can be in place before you disclose anything, and a scientist replies within two business days.
Toshi Maruyama, MD, PhD
Chief Scientific Officer and Chief Operations Officer
30+ years in antibody discovery — Scripps Research (Dennis Burton lab), Alexion Antibody Technologies, Calmune.
Isolated KZ52, the first human monoclonal antibody shown to neutralize Ebola virus.
Developed the humanized anti-CD200 antibody samalizumab at Alexion, later advanced into clinical trials.
MD, PhD — Tokyo Medical and Dental University.
CJ Okumura, PhD, MBA
Chief Executive Officer and President
Postdoctoral fellow in the Nolan lab at Stanford University and at the RIKEN Research Center for Allergy and Immunology.
Senior business-development leadership at BioLegend before co-founding Abwiz Bio.
DDS, PhD — Tokyo Dental College; MBA — UC San Diego, Rady School of Management.
Have a target like this?
Tell us the antigen and what has failed so far. A scientist replies within two business days — no sales pitch, NDA first if you prefer.
Ask a scientist →or email info@abwizbio.com