Human/Mouse Myl9/12 (F6) rabbit mAb

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100 µg(1151) $349.00

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Product Overview

Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads.

Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.(1) This rabbit monoclonal antibodies against Myl9/12 (clone F-6) is made by immunization with N-terminal peptide of Myl9.

Product Details
More Information
Applications Functional Assay, IHC, ELISA
Clone AWBMyl9F6 (F-6)
Format Unconjugated
Validated Reactivity Human, Mouse
Cross Reactivity Antibody may react with the same target protein from other species sharing the same sequence.
Detection Anti-Rabbit IgG
Clonality Monoclonal
Immunogen N-terminal peptide of Myl9
Formulation 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Isotype Rabbit IgG1k
Preparation Protein A+G
Recommended Usage 1µg/mL – 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
Storage -20ºC
References 1. K. Hayashizaki, M. Kimura, K. Tokoyoda, et al. (2016) Science Immunology, 1:eaaf9154.
2. "Entrez Gene: myosin".
Cell Culture Products
Anti-human/mouse Myl9/12 Abwiz antibody AWBMyl9F6 (Cat. #1151) shows strong and specific tissue staining by immunohistochemistry.
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