Human/Mouse Myl9/12 (F6) rabbit mAb

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100 µg(1151) $349.00

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Product Overview

Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads.

Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.(1) This rabbit monoclonal antibodies against Myl9/12 (clone F-6) is made by immunization with N-terminal peptide of Myl9.

Product Details
More Information
Applications Functional Assay, IHC, ELISA
Clone AWBMyl9F6 (F-6)
Format Unconjugated
Cross Reactivity Antibody may react with the same target protein from other species sharing the same sequence.
Detection Anti-Rabbit IgG
Formulation 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Immunogen N-terminal peptide of Myl9
Isotype Rabbit IgG1k
Preparation Protein A+G
Validated Reactivity Human, Mouse
Clonality Monoclonal
Recommended Usage 1µg/mL – 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
References 1. K. Hayashizaki, M. Kimura, K. Tokoyoda, et al. (2016) Science Immunology, 1:eaaf9154.
2. "Entrez Gene: myosin".
Storage -20ºC
Cell Culture Products
Anti-human/mouse Myl9/12 Abwiz antibody AWBMyl9F6 (Cat. #1151) shows strong and specific tissue staining by immunohistochemistry.
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