SARS-CoV2 LxC1-G4 human neutralizing mAb

Catalog
2546
Select Your Size Price
200 uL (0.5 mg/mL)(2546-200) $475.00
20 uL (0.5 mg/mL)(2546-20) $175.00
$175.00
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Note

20 μL is enough antibody for at least 20 Western blots. 

Product Overview
Description
Product Details
More Information
Special Notice Avoid multiple freeze and thaw.
Applications Functional Assay, ELISA
Clone LxC1-G4
Format Unconjugated
Validated Reactivity Other
Cross Reactivity No
Detection Anti-Human IgG
Clonality Monoclonal
Immunogen A recombinant SARS-CoV-2 spike protein containing RBD.
Formulation 1X PBS
Isotype Human IgG1 Kappa
Preparation Protein A
Recommended Usage Experimental conditions may be optimized.
Storage -20ºC
Images
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. The bound antibodies were detected with Peroxidase AffiniPure Goat Anti-Human IgG, Fcγ fragment specific (Jackson Immuno Research Catalog#109-035-098) or Peroxidase AffiniPure Goat Anti-Rabbit IgG, Fc fragment specific (Jackson Immmuno Research Catalog#111-035-046). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudovirus neutralization test. LxC1-G4 reacts to WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon. Recombinant Human ACE-2 Fc Chimera Protein (ACE2-Fc) (R&D Systems Catalog#10544-Zn) and C-A11 (Catalog#2536) were included as controls.
Cell Culture Products
Spike protein trimers were coated at 2 µg/mL and incubated with serially diluted antibodies. ACE2-Avitag protein (Acro Biosystems AC2-H82E6) was added to 0.037 µg/mL and the bound ACE2 was detected with High Sensitivity StreptAvidin-HRP (Thermo Fisher Scientific Catalog# 21130). LxC1-G4 (Catalog#2546) is a humanized antibody developed from a SARS-CoV-2 neutralizing antibody hN2F that showed effective neutralization of WT, Alpha, Beta, Gamma in a live virus neutralization test and a pseudo virus neutralization test LxC1-G4 reacts with WT, Alpha, Beta, Gamma, Kappa, Delta, and Epsilon.
Cell Culture Products
ACE2-Fc protein (Acro Biosystems AC2-H5257) was coated at 2 µg/mL and incubated with serially diluted antibody mixed with Biotinylated SARS-CoV-2 spike trimer (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N), His, Avitag (Acrobiosystems SPN-C82Ec) (1 ng/mL) and the bound spike trimer was detected with High Sensitivity StreptAvidin-HRP (Thermo Fisher Scientific 21130). LxC1-G4 effectively blocked the binding of spike trimer to ACE2 protein (IC50 = 30.49 ng/mL and IC80 = 60.61 ng/mL).