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Purified anti-phospho-Histone H3 (Ser10) rabbit mAb

phospho-Histone H3 (Ser10)

Flow cytometric analysis of Hela cells, secondary antibody only negative control (blue) or untreated (red) or treated with nocodazole (green) using Phospho-Histone H3 (Ser10) antibody HisH3S10-4B6. Cat. #2061.

Catalog Number: 2061
Clonality: Monoclonal
Applications: WB, Flow Cytometry
Reactivity: Human
Format: Purified
Conjugate: Unconjugated
Catalog Number: 2061
Clone: HisH3S10-4B6
Isotype: Rabbit IgG1κ
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser10 of human phospho histone H3
Reactivity: Human
Cross Reactivity: Same target other species with same sequence
Preparation: Protein A+G
Formulation: 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Storage: -20ºC
Applications: WB, Flow Cytometry
Recommended Usage: 1- 0.1 µg/ml. Optimum concentration should be determined by the user.
Detection: Anti-Rabbit IgG


Histone H3 is one of the five main histone proteins involved in chromatin structure modification in eukaryotic cells. Histone proteins are highly post-translationally modified, including acetylation, phosphorylation, methylation and ubiquitination. Phospho histone H3 is the most extensively modified of the five histones. Phospho histone H3 is primarily acetylated at Lys9, 14, 18 and 23. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10, Ser28 and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis. The term "Histone H3" alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state.



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This product was added to our catalog on Monday 26 September, 2016.

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Size(s) Price
20 ul (0.5mg/ml, more than 20 western blots) (2061S) $175.00 
200 ul (0.5mg/ml, more than 200 western blots) (2061) $475.00 

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