||N-terminal peptide of Myl9
||Antibody may react with the same target protein from other species sharing the same sequence.
||PBS, 0.09% Azide
||Functional Assay, ELISA, IHC
||Optimum concentration should be determined by the user.
Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads.
Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.(1) This rabbit monoclonal antibodies against Myl9/12 (clone F-6) is made by immunization with N-terminal peptide of Myl9.
1. K. Hayashizaki, M. Kimura, K. Tokoyoda, et al. (2016) Science Immunology, 1:eaaf9154.
2. "Entrez Gene: myosin".
This product was added to our catalog on Wednesday 07 September, 2016.