| Catalog Number: |
1151 |
| Clone: |
AWBMyl9F6 (F-6) |
| Isotype: |
Rabbit IgG1κ |
| Immunogen: |
N-terminal peptide of Myl9 |
| Reactivity: |
Mouse,Human |
| Cross Reactivity: |
Antibody may react with the same target protein from other species sharing the same sequence. |
| Preparation: |
Protein A+G |
| Formulation: |
PBS, 0.09% Azide |
| Storage: |
2-8ºC |
| Applications: |
Functional Assay, ELISA, IHC |
| Recommended Usage: |
Optimum concentration should be determined by the user. |
| Detection: |
Anti-Rabbit IgG |
Description:
Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads.
Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.(1) This rabbit monoclonal antibodies against Myl9/12 (clone F-6) is made by immunization with N-terminal peptide of Myl9.
References:
1. K. Hayashizaki, M. Kimura, K. Tokoyoda, et al. (2016) Science Immunology, 1:eaaf9154.
2. "Entrez Gene: myosin".
This product was added to our catalog on Wednesday 07 September, 2016.
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